Essay example --

Free etymons play an important role in some(prenominal) biological influencees such as cell signaling and redox regulation. However, extend exposure to free radicals leads to oxidative damage. Subsequently, it has been implicated in the progression of some(prenominal) disorders like cancer, cardiovascular disease, neurological disease, pulmonary disease, rheumatoid arthritis, nephropathy, ocular disease and pre-eclampsia. The antioxidant defense system within the body whitethorn confer surety to oxidative damage by scavenging free radicals. Antioxidants also whitethorn be obtained from dietary sources/ supplements. The efficacy of antioxidant intake on initiation and progression of degenerative diseases will be reviewed.IntroductionOxygen is an element that is crucial for the life of life on earth. It is paradoxical that this indispensable element can make water harmful effects in humans under certain circumstances. much of the detrimental consequences of oxygen are attri buted to its ability to form free radicals (1) . A free radical is a reactive molecule that contains at least one unpaired electron in its outer orbit, and is capable of commutative existence (2).Accumulation of these molecules in the body results in oxidative stress, a process by which physiologically important molecules such as carbohydrates, proteins and lipids are alter (3). However, the body can employ antioxidants to impede the threat of free radical attack (4).Antioxidants are potent scavengers of free radicals (1). They function by donating an electron to a free radical or by eliminating initiators of free radicals (5). Antioxidants may be classified as endogenous or exogenous depending on their mode of acquisition by the body (1). Endogenous antioxidants are by nature produced by t... ...ment dosage and duration of treatment. Moreover, a host of lifestyle behaviors are responsible for determining the health of individuals. Antioxidant intake in combination with fleshly activity, and alcohol and tobacco moderation may yield profound benefits in disease management. Thus, multifactorial interventions may serve as alternative strategies in disease management. Finally, investigations on the effects of nutrients in isolation may deliver the goods valuable information regarding its mode of action, but do not bring in the phenomenon of total diet. The intrinsic nature of diet is characterized by several interactions mingled with bioactive dietary components, some of which still remain unexplained. Hence, antioxidant supplements must be positively charged with caution and the use of antioxidant rich foods as disease prevention agents may hold promise in future clinical trials.